Hepatic Fgf21 Expression Is Repressed after Simvastatin Treatment in Mice.
Fibroblast growth factor 21 (Fgf21) is a hormone with emerging beneficial roles in glucose and lipid homeostasis.The interest in Fgf21 as a potential antidiabetic drug and the factors that regulate its production and secretion is growing.Statins are the most widely prescribed drug for the treatment of dyslipidemia.However, the function of statins i